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Obstetrics & GynaecologyContraceptionhigh-yield

Contraceptive methods compared

Mechanism, key contraindications and best-fit patient for every major contraceptive method in one comparison.

6 min read · updated 2026-08-24

The logic before the list

Every method blocks fertilisation at one of three points: stop ovulation (hormonal suppression of the axis), block the sperm (barrier or a hostile cervix/endometrium), or prevent implantation (copper toxicity, endometrial thinning). Fix the mechanism first and the contraindications fall out on their own — anything oestrogen-containing carries a thrombosis and oestrogen-dependent tumour risk, so those are the traps.

Method-by-method

MethodMain mechanismKey contraindicationsSuits whom
Combined oral pill (COC)Oestrogen + progestogen suppress FSH/LH → no ovulation; also thickens mucus, thins endometriumMigraine with aura, smoker >35 y, VTE/thrombophilia, breast cancer, uncontrolled HTN, active liver disease, <6 wk postpartum/breastfeedingYoung, non-smoking woman wanting cycle control, less dysmenorrhoea, acne benefit
Progestogen-only pill (POP)Thickens cervical mucus, thins endometrium; ovulation blocked only partiallyCurrent breast cancer; needs strict same-time daily dosingBreastfeeding mother, smoker >35 y, or anyone in whom oestrogen is barred
Copper IUCD (Cu-T 380A)Copper ions are spermicidal + inflammatory endometrium → blocks fertilisation & implantationPelvic infection/PID, undiagnosed bleeding, distorted cavity, Wilson disease, pregnancy, copper allergyWoman wanting long-acting, non-hormonal cover; also emergency contraception up to 5 days
LNG-IUS (hormonal IUD)Local levonorgestrel thins endometrium, thickens mucusCurrent breast cancer, pelvic infection, undiagnosed bleedingWoman with menorrhagia (turns it into a treatment), oestrogen contraindicated
Implant (etonogestrel)Progestogen suppresses ovulation for 3 yCurrent breast cancer, undiagnosed bleedingWants highest efficacy, "fit-and-forget", poor pill compliance
Injectable (DMPA)Progestogen suppresses ovulation, given 3-monthlyCurrent breast cancer; caution — reversible bone density loss, delayed return of fertilityWants privacy/compliance-free cover, near completed family
Barrier (condom/diaphragm)Mechanical block of spermLatex allergy (use polyurethane)Anyone needing STI protection; new/multiple partners
Emergency contraceptionLNG 1.5 mg or ulipristal delays ovulation; copper IUCD is most effectiveEstablished pregnancy (it does not disrupt it)After unprotected sex — LNG within 72 h, IUCD within 120 h

The exam traps

  • Copper IUCD is the most effective emergency method and also the only one that provides ongoing cover.
  • DMPA is the method linked to reversible loss of bone mineral density and the longest delay in fertility return.
  • COC in a migraine-with-aura patient sharply raises stroke risk — an absolute bar.
  • Postpartum breastfeeding: avoid oestrogen; POP/implant/DMPA are safe.

Pearl: match mechanism to the contraindication — if oestrogen is dangerous (smoker >35, migraine with aura, VTE, breastfeeding), reach for a progestogen-only or copper method every time.

Sources

  • DC Dutta's Textbook of Gynaecology, 8e
  • Park's Textbook of Preventive and Social Medicine, 27e